But here’s an interesting way to look at that risk. Let’s say that Diane, who is truly uninfected (ie, HSV-2 seronegative), meets Bob who has HSV-2. Bob tells Diane about his infection. He offers to use condoms every time they have sex, take daily antiviral therapy, and agrees to try to be aware of any symptoms that may signal the beginning of an outbreak. Diane says that she just can’t handle any risk, even though she really likes Bob. So she says goodbye and moves on. Then she meets Bill. She asks him right away whether he has herpes because now she’s really worried about getting infected. He replies that he’s “not that kind of guy” and is certain that he is not infected, only he really is (as approximately 1 in 4 adults are) but doesn’t know it. Now we know that Bill is shedding virus at the same rate as Bob, but because he is unaware of his infection and doing nothing about it, he is more likely to infect Diane than Bob ever was. But Diane likes Bill’s answer. She has sex with him with birth control pills instead of condoms, and within 2 months is infected with HSV-2. She’s the one sitting in your exam room, waiting for the news. And the circle continues.
By Importance and Practicalities of Patient Counseling in the Prevention and Management of Genital Herpes - Terri Warren (via suffered-in-silence)